2025
HIF-1α and VEGF Immunophenotypes as Potential Biomarkers in the Prognosis and Evaluation of Treatment Efficacy of Atherosclerosis: A Systematic Review of the Literature
Vageli D, Doukas P, Georgiou D, Prokopiou M, Ladaki N, Papadopoulou A, Doukas S, Zacharouli K, Makaritsis K, Ioannou M. HIF-1α and VEGF Immunophenotypes as Potential Biomarkers in the Prognosis and Evaluation of Treatment Efficacy of Atherosclerosis: A Systematic Review of the Literature. Frontiers In Bioscience-Landmark 2025, 30: 27004. PMID: 39862086, DOI: 10.31083/fbl27004.Peer-Reviewed Original ResearchConceptsVascular endothelial growth factorTreatment efficacyHIF-1aUpregulation of pro-inflammatory moleculesPotential biomarkersMitogen-activated protein kinaseAttenuation of atherosclerosis progressionOverexpression of vascular endothelial growth factorVascular endothelial growth factor protein expressionIncreased VEGFVascular endothelial growth factor overexpressionLipopolysaccharide-induced tumor necrosis factor-alpha factorAtherosclerosis progressionSystematic reviewTumor necrosis factor-alphaVascular smooth muscle cellsExposure to methamphetamineAdenosine receptor antagonistHypoxia-inducible factor-1 alphaNecrosis factor-alphaNitric oxideChronic exposure to methamphetamineEndothelial growth factorSmooth muscle cellsEvaluation of treatment efficacy
2023
Gastric cancer after Bariatric Bypass Surgery. Do they relate? (A Systematic Review)
Doukas S, Doukas P, Vageli D, Broder A. Gastric cancer after Bariatric Bypass Surgery. Do they relate? (A Systematic Review). Obesity Surgery 2023, 33: 1876-1888. PMID: 37041375, DOI: 10.1007/s11695-023-06567-6.Peer-Reviewed Original ResearchConceptsBariatric bypass surgeryBypass surgeryGastric cancerGastric cancer risk assessmentGastric bypass surgeryH. pylori infectionGastric cancer surveillanceCancer-promoting factorGastric cancer casesCancer risk assessmentBile refluxMorbid obesityTobacco smokingPylori infectionCancer surveillanceRisk factorsCancer casesFamily historyEffective treatmentSurgeryAdvanced stageSystematic reviewCancerFurther investigationObesity
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